RUO viral vector products

We offer a comprehensive range of viral vectors for research and preclinical applications, including standard viral vectors with various promoters, selection markers, and reporters, as well as inducible systems. They are particularly useful for transducing both dividing and non-dividing cells, making them suitable for immunotherapy, cell therapy, and gene addition strategies. Applications include CAR-T therapies, the genetic modification of hematopoietic stem cells (HSCs), and the treatment of monogenic diseases​. We offer the FlashRNA technology for transient gene delivery without integration of the genome, which increases the risk of insertional mutagenesis. It is an RNA delivery system for coding and non-coding RNAs, ideal for applications such as RNA vaccination and regenerative medicine.
Our custom viral vector service can be tailored to your specific needs, all within a 3-week turnaround.

The difference between standard and customized viral vectors offered by Flash Therapeutics lies in their specific tailoring for applications. Available immediately, our standard products are pre-designed for general purposes with a wide range of common features to address various research needs (screening, in vivo cell tracking, transduction efficiency assessment, specific cell populations, or organelle labeling). On the other hand, our customized products are fully tailored to your project needs, offering flexibility from gene synthesis to viral vector production, including the generation of a custom transfer plasmid with the expression cassette of your choice, based on the therapeutic requirements. We can offer different concentration and purification grades for viral vector production, according to your needs. This service can be completed in just 3 weeks.

We encourage you to contact our team of vectorology experts to discuss the specifics of your project. Whether you need standard products or customized solutions, our team is committed to delivering scientific excellence and ensuring the success of your project. You can reach us directly via our “Contact Us” page or at the following email address: project@flashbiosolutions.com. We’ll be happy to answer your questions by email or schedule a meeting.

Viral vectors offer a versatile platform for a wide range of research and preclinical applications.
Some of the key areas include Gene Delivery and Expression for studying gene function, gene editing, and genetic disease modeling; CRISPR/Cas9 Gene Editing for precise gene editing, allowing researchers to knock out or correct specific genes of interest in pre-clinical models; CAR-T Cell Development for enabling the development of pre-clinical CAR-T therapies targeting various cancers; Cancer Vaccine Development to transduce dendritic or tumor cells to generate potent immune responses, facilitating the development of therapeutic cancer vaccines in pre-clinical studies; Modeling Genetic Disorders to introduce disease-causing mutations in animal models to study the pathology of genetic disorders such as cystic fibrosis, sickle cell anemia, and neurodegenerative diseases; Stem Cell Research for gene delivery in hematopoietic stem cells (HSCs), aiding in the development of gene therapy strategies for diseases like β-thalassemia, sickle cell disease, and immunodeficiencies ; Immunomodulation to deliver genes that modulate immune responses, exploring therapies for autoimmune diseases such as multiple sclerosis and rheumatoid arthritis.

Using our viral vectors for research and preclinical applications offers several key benefits:
High Potency and Purity: Our exclusive production platform ensures that both standard and customized viral vectors have optimal purity and potency, with high titers that can exceed 10^9 IG/mL. This translates into up to 100% transduction efficiency not only on immortalized cell lines, but also on primary cells and stem cells.
Optimized Production: We customize our purification and concentration processes based on your target cell type, ensuring high titer and exceptionally pure viral particles for the most sensitive cells.  This quality allows to fully maintain target cell viability, phenotype, and proliferation capacities.
Scale-up performance: Our vectors and production processes are designed for controlled scaling, enabling a smooth transition from discovery phases to therapeutic phases.

We understand how critical deadlines are for your research projects. That’s why we offer standard vectors available immediately and custom vectors with lead times starting from 3 weeks, while guaranteeing strict quality and safety standards for our products.

Products can be kept for more than 10 years when stored at -80°C after receipt.